Noopept Review: Side Effects, Dosage and Beginner’s Guide

Okay, first thing’s first.

Noopept is one of my favorite nootropics, hands down.

Sure, it doesn’t have the same reliable kick as caffeine or long-term focus effect as Modafinil. But it’s incredibly cheap given the small dose needed to get the maximum effects. That and its effects are quite lovely.

Before I dive into each one, let’s take a step back and see how this wonderful little nootropic powder came into existence…

What is Noopept? (A Short History)

Noopept is a nootropic supplement originally discovered and synthesized in Russia, where it was promoted as a smart drug and cognitive enhancer.

It is derived from the racetam family of drugs and shares similar mechanisms of action.

Piracetam was the first nootropic discovered way back in 1964 (yes, exactly the year when Muhammad Ali became the world heavyweight champion) and it is one of the biggest selling nootropics even after 50 years.

Okay, so why Noopept and not Piracetam?

Well, first off, Noopept is 100 to 1000 times more potent than Piracetam (for equivalent doses). Another reason is that Noopept is a smart drug and a more recent and thoroughly researched version of older nootropics for better memory (such as Piracetam).

Studies have shown Noopept to be neuroprotective and memory-enhancing in various tests. It is also said to be independently verified as the purest nootropic in Europe.

Unusually for a peptide-derived compound, Noopept displays both high oral bioavailability and good blood–brain barrier penetration in rats and human. Studies have shown promising results with potential application in the treatment of Alzheimer’s disease.

Noopept also helps grow new brain cells. How awesome is that?

It stimulates the expression of NGF and BDNF in rat hippocampus which is associated with reduction and prevention of neuronal degeneration.

The release of Brain-Derived Neurotrophic Factor (BDNF) helps keep our neurons healthy and alive, as well as strengthening the growth and differentiation of new neurons and synapses.

Another cool thing Noopept does is, it stimulates the AMPA and NMDA receptors and their pathways. Both of these receptors are glutamatergic receptors which play roles in memory and thought processes. This is why it is ideal for those afflicted with Alzheimer’s and other neurodegenerative disorders.

This little nootropic doesn’t stop there, it actually lowers anxiety by interacting with Dopamine receptors D2 and D3 as well as nicotinic ACh receptors.

Not only that but Noopept also has both an anti-inflammatory benefit as well as antioxidant properties.

How Noopept Works

Improved Learning and Memory Recall

Noopept energizes the neurotransmitters in the brain, and enables better communication within the neural network.

To be more specific, Noopept boosts Acetylcholine, which is one of the most important neurotransmitters in the brain influencing both the central nervous system and peripheral nervous system.

This in turn, sends signals to the important neurons in the brain and ultimately improves reasoning, recalling, and problem-solving skills.

Improves brain health

Just like Vitamin E is for your skin, Noopept serves as a powerful antioxidant for your brain.

Its neuroprotective properties help protect your brain cells from physical damage, and helps you to focus harder for longer durations. By keeping your brain cells protected, it helps improve your overall brain health.

To improve learning?

Noopept boosts Nerve Growth Factor (NGF) and Brain-Derived Nerve