Phosphatidylserine

Phosphatidylserine…

(say that three five times fast)

In addition to being difficult to pronounce, this amino acid derivative is believed to influence cognitive abilities.

The buzz around it hails it as a memory enhancer, Cortisol controller, and all-around neuroprotective agent. Proponents say it can help with depression, stress, athletic performance, ADHD, and a wide range of neurological conditions.

Studies only support some of the claims, however. Could the hype surrounding its supposed abilities be overblown? Let’s explore.

What is Phosphatidylserine?

Phosphatidylserine is a naturally occurring phospholipid that is produced in the body, The majority of human supply, though, comes from food sources.

When supplemented, it is believed that Phosphatidylserine provides protection against age-related cognitive decline and Alzheimer’s.

Some believe, however, that because of its function within the body (cell-to-cell communication, among other things) and prevalence in neural tissue might grant it some other abilities as well.

Proponents argue that in otherwise healthy brains, it can add a cognitive boost akin to many popular nootropics. Those looking for mood enhancement believe its effects on cortisol reduce stress and promote a happier mood.

Some athletes believe it can boost their performance by helping with blood pressure, heart rate, and muscle soreness. The list goes on, as there are at least twenty separate health benefits that have been ascribed to this chemical.

Evidence supporting many of them, though, is scant. Currently, the only well-researched effects of Phosphatidylserine are on cognition, cognitive decline, cortisol, and ADHD.

Some others have mixed results from studies, and many more have no evidence backing their claims whatsoever.

It’s legal to buy, and those that have tried it say a 200-400 milligram dose is usually the best way to achieve its acute effects.

The preventative effects are believed to result from daily supplementation in the amount of approximately 300 milligrams.

I’ll be honest, I’m going in skeptical that Phosphatidylserine provides anything beyond some slight long-term benefits, and the acute effects people rave about are likely the placebo effect working in full force.

Still, I’ve been wrong before, so I decided to give this one a go.

Other Names

The list is extensive and includes entries such as BC-PS, Phosphatidyl Serine, PS, and Pt