The Best Nootropic Stack to Replace Adderall & Ritalin

Nowadays, you don’t visit a new restaurant until you’ve looked up Yelp reviews or asked your friends about their favorite places.

The same rules should apply when you’re in the market for a good nootropic stack.

Now, when it comes to food preferences, what one person likes may not be something that you like. But at least it gives you an idea of what’s out there.

The same is true of nootropics, everyone is different and everybody responds differently to nutraceutical combinations.

It all comes down to personal preference and needs. Nevertheless, in the following guide, I will teach you how to put together the best stack for you.

You’ll learn how to build the stack that suits your specific requirements.

A lot of companies offer “proprietary” blends that they advertise as the complete, perfect stack for everyone. When it comes to nootropics, this is a bit of a red flag.

Any brand who claims to have the best stack — but who does not share the dosages of each ingredients — should be approached with discretion.

To be clear: on Corpina, I’m not selling anything. I’m here to explore and recommend nootropics that I’ve tried myself, and which may be able to assist you in your quest to enhance your mood, boost your performance and so on and so forth.

So let’s get started.

The 6 Best All-in-One Nootropic Stacks

Despite the extensive list of options I am about to offer for building a DIY stack, many of my readers will probably want pre-made stacks that are entirely done-for-you (whether they be proprietary or not).

Sometimes, it’s just more convenient to take one supplement that rolls everything into one.

Oftentimes, it’s much more affordable to buy a proprietary formula that contains multiple ingredients than it is to go out and purchase each supplement on its own.

If you’re absolutely insistent upon going with a pre-formulated stack, here are some recommendations for you to choose from.

NameEffect RatingPriceWhere To Buy
Qualia☆☆☆☆☆$$$$Get Qualia
Mind Lab Pro☆☆☆☆$$$Get Mind Lab Pro
Alpha Brain☆☆☆$$$Get Alpha Brain
TruBrain☆☆☆☆$$$Get TruBrain
OptiMind☆☆☆☆$$Get OptiMind

1. Qualia

I highly recommend this particular blend. A unique product from the people at the Neurohacker Collective, Qualia is a split stack that comes in two separate bottles, one that you take during early morning fasting and the other for after you eat.

Qualia contains Taurine, Lion’s Mane, Uridine Monophosphate, ActivAMP Gynostemma Pentaphyllum Extract and Acetyl-L-Carnitine, among many, many other ingredients, all for optimal mental performance.

As you may have heard, Uridine Monophosphate promotes a positive mood and assists in the areas of motivation and focus.

ActivAMP Gynostemma Pentaphyllum Extract is a highly concentrated derivative of the adaptogenic herb Gynostemma Pentaphyllum which aids in weight loss, relaxation and mood improvement. It is often used as an herbal alternative to prescription antidepressants.

Unlike other brands, the folks at Neurohacker Collective have gone to great lengths to prepare a stack that gives the user the exact amounts of each ingredient for ultimate efficacy and brain health.

Click here to order Qualia, and use code CORPINA to get 10% off.

2. Mind Lab Pro

Mind Lab Pro is called the “universal nootropic” for a good reason. Because it contains eleven research-backed ingredients that have been used for thousands of years all over the globe.

Ancient cultures knew the value of these popular folk medicines and thanks to companies like Opti-Nutra, the Western world is waking up to their myriad benefits.

Mind Lab Pro is said to be able to boost memory, increase energy, increase creativity, improve mood, relieve stress and fight aging in just two capsules. It is able to achieve all of this courtesy of its unique and diverse formula.

Mind Lab Pro contains Citicholine, Phosphatidylserine, Bacopa Monnieri, Lion’s Mane Mushroom (Full Spectrum Extract), Pterostilbene, Tyrosine, L-Theanine, Rhodiola Rosea, Vinpocetine, Vitamin B6 and Vitamin B12.

Citicholine is an impressive supplement that has been clinically proven to treat cognitive impairment. It is commonly implemented in the treatment of ADHD, anxiety disorders and Parkinson’s disease.

Pterostilbene possess antioxidant enhancing mechanisms which can be beneficial in a number of areas. Studies suggests that it can help to diminish esophageal cancer cells and reduce oxidative stress.

If Qualia is outside your price range, I highly recommend MLP as your go to all-in-one nootropic stack.

3. Alpha Brain

This one’s got a solid reputation among consumers, but it’s not my absolute fave since it contains fillers and is pretty expensive.

One 90 count bottle costs a whopping $67.96. If you have money to spend, Alpha Brain might be right for you.

Alpha Brain works by stimulating the release of acetylcholine in your brain. It achieves this by providing raw choline via Alpha GPC content, an excellent source of choline.

But is Alpha Brain really effective? And is Alpha Brain worth the money?

User reviews question the legitimacy and value of this product with one user on the Joe Rogan sub-Reddit writing, “I went through a whole bottle a few years ago…and nothing. Didn’t feel even the slightest bit different.

Tried high doses too. No crazy dreams either. Maybe I’m just not sensitive enough to feel what’s going on with my body. But whenever I hear someone on a podcast go off on how they swear by it, I can’t help but roll my eyes.”

Another user wrote, “Even if alpha brain worked, for most it’s far too expensive to use on a regular basis, let alone at the dose Rogan says (4 at a time).”

If you still decide to go with this stack, you should know what’s in it. Each bottle contains Cat’s Claw, Bacopa Monnieri, Huperzia Serrata and Oat Straw.

My verdict: Alpha Brain does indeed work well, but the benefits may not be worth the price.


CILTEP contains a small number of ingredients and it’s far from cheap for what you’re getting in each capsule. The main ingredients are Artichoke Extract, Forskolin, L-Phenylalinine, ALCAR and Vitamin B6.

Billed as “the most trusted nootropic,” CILTEP is said to safely enhance the brain’s ability to form vivid, long-lasting memories and sharpen mental focus as well as motivation.

The problem is, there is an inadequate amount of medical research to support any claims about its ingredients.

While artichoke extract has long been used as a natural remedy, there is no scientific evidence to back up its purported benefits.

Yes, ALCAR or Acetyl-L-Carnitine has been known to be beneficial to those afflicted with anxiety and depression, but most of the scant ingredients in this formula are dubious at best.

On a more positive note, if you’re looking for a milder blend, this may be the stack for you. It has a mild kick and may indeed have long term nootropic benefits.

That’s the upside. And the downside? There are two that come to mind.

First, when you consider the wealth of ingredients present in competitors’ blends, CILTEP seems to come up short in terms of effective and versatile formulas. You may be better off buying the ingredients individually from reliable supplement vendors like NOW Foods.

Second, some users, including myself, have experienced a sort of short-but-intense depression after more than a week of daily CILTEP usage.

It’s not clear what causes this effect, but reports on Longecity and Reddit suggest that CILTEP “burns out” your natural serotonin, thus giving you the blues.

Nevertheless, I still take CILTEP occasionally for the possibility of inducing long-term potentiation.

5. TruBrain

This one’s a good all-around option for beginners. It’s safe and contains high quality ingredients. After a few months of consecutive use, I think it’s worth the price.

Designed to boost mental performance and vanquish stress, TruBrain was developed by UCLA-trained neuroscientists who allege that it can help the user to power past stress and overcome mental blocks.

Users on Reddit have reported great experiences using TruBrain with one poster writing, “Trubrain’s stack does wonders for ADHD and depression, and their customer service is amazing.”

And for those who don’t like taking “horse pills,” the company also offers TruBrain as a “think drink” which comes in a variety of delicious flavors.

Another interesting thing about TruBrain is its dedication to ongoing R & D. The company relies on a team of CEOs, artists and lawyers (as well as other forward-thinking professionals) to research data patterns. This enables them to better determine what they could be doing better.

It contains Piracetam, CDP-Choline, Magnesium, Acetyl-L-Carnitine, Pramiracetam, L-Theanine and Tyrosine, all of which are excellent ingredients for a cognitive enhancement stack.

6. OptiMind

Optimind is a cognitive enhancer that is meant to enhance focus, maintain memory function and increase concentration. Like Mind Lab Pro, Optimind has a wide range of ingredients with a total of twelve active ingredients in each supplement.

Users of Optimind have called it “amazing,” effective and “safe.” Personally, I like this one because you’re getting a lot of bang for your buck.

Each Optimind supplement contains GABA, Vitamin D3, Phosphatidylserine, Caffeine, Alpha-Lipoic Acid, Tyrosine, Taurine, Huperzine A, Sulbutiamine, Vitamin B12, Bacoside A and Vinpocetine.

The ingredient of note here is Bacoside A which stimulates neurotransmitters and is believed to be capable of reducing oxidative stress and treating epilepsy.

As a whole, Optimind is an impressive stack and one that has been more well-received than others on the market. A 32 count bottle sells for $43.31 which places it at a fair middle of the road price point.

Best Nootropic Stack for Mental Performance

Enhancing one’s cognition is not as difficult as it might seem. You don’t have to be Bradley Cooper in Limitless to improve your mental performance and boost your cognitive abilities.

Maybe you’re looking for one or more of the following:

  • Increased focus and concentration
  • Mood enhancement
  • Creativity