How To Avoid the Side Effects of Phenibut Withdrawal

Sounds simple enough, right?

Not quite.

Taking phenibut on a totally empty stomach (unless before bed) or with alcohol are the number 2 and 3 causes of phenibut hangover, after overdosing.

Here are a few simple tips for avoiding a painful next-day phenibut hangover.

1.Take Less Phenibut!

Many users report that Phenibut’s effects can be fully achieved at dosages as little as 200 mg (in men weighing 200lbs — roughly 5% of the recommended dose!).

Doses between 200 and 500 milligrams moderately inhibit anxiety and will help you open up around others in social situations. Talking and interacting with people becomes easier and more enjoyable.

2. Do Not Combine Phenibut With Certain Drugs

Always be aware of potential drug interactions when taking substances of any kind, especially when the drug’s effects aren’t well documented. In many cases, additional drugs will decrease the threshold phenibut dose and potentiate random, unwanted side effects of the drug.

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Phenibut can amplify any of the following drugs

Phenibut amplifies some of the effects of anesthetics:

  • ethers
  • chloral hydrate
  • barbiturates
  • diazepam
  • alcohol
  • morphine

What’s more, it interacts with related drugs, such as opiates and GHB.

Members of the Strength.com community unanimously report that taking phenibut with mild or heavy opiates leads to significantly enhanced enhanced effects.

Avoid these combinations

In contrast, taking phenibut with some stimulants like amphetamines and caffeine will often blunt the anxiolytic effect (in the short term), leaving users agitated and anxious later on: a lose-lose scenario.

Such interactions can lead to panic attacks and exacerbate the painful phenibut withdrawal. Phenylethylamine (PEA) and many of its derivatives are potent stimulants and should also be avoided.

Many reports indicate that phenibut reacts negatively with epilepsy medications. If a patient is diagnosed with any type of chronic illness or if s/he is taking any kind of special medication, then s/he should not take phenibut whatsoever.

If drug combinations are not your concern, turn to a simple trick for warding off the hangover…

3. Take Phenibut With Food And Ample Liquids

Consume phenibut with a large meal, or mix the powder in water or juice to stave off hangover symptoms.

During your kick it is important to eat right, stay hydrated and really take care of your body. Don’t be afraid to pamper yourself!

4. Take a few days off between doses…

You might have heard that replacing the standard breakfast-lunch-dinner combination with five small meals at shorter time intervals is an effective way to lose weight.

While the research on this dieting technique is inconclusive, it’s an effective way to mitigate phenibut’s undesirable morning-after side effects.

Higher does (1 – 1.5 grams) tend to be more sedating, especially when taken all at once. In my experience spreading a 1.5 gram dose out over a few hours can lead to the most positive effects especially in terms of social interaction and anxiety reduction.

Avoid doses larger than 3 grams (again, especially if taken all at once) because they can cause a hangover of sorts the next day. These dosages are from user experiences only and many people respond differently, so keep that in mind when planning your dosing regiment.

5. Use Other Beta-Blockers to Taper Phenibut Withdrawal

A slow but effective taper should be done in order to successfully come down phenibut, both in the short- and long-term; however, this can be hard to do for some people, especially if they’re doing it on their own.

Luckily there are other beta-blocker options like these, which can make the withdrawal symptoms much less severe.

First and foremost is a drug called baclofen, which can be taken until phenibut’s withdrawal period has passed. This is a successful method favored by many individuals who take phenibut to reduce social anxiety.

Baclofen is often prescribed to people to help them recover from GHB withdrawals. Ask your doctor about using Baclofen as a short-term replacement to help you get over phenibut withdrawal (only long enough so that you don’t develop an addiction to the baclofen!).

If you’re not comfortable discussing phenibut use with your doctor, then consider telling him or her the white lie that you need help getting off of GHB and that you would like to use baclofen to do so (rather than mentioning phenibut and possibly not even getting prescribed any baclofen).

Baclofen acts in a similar manner to phenibut in that it occupies the same receptor (GABA), which is why it works so well at relieving phenibut’s withdrawals.

The risk of developing an addiction to baclofen is nearly high as the potential for addiction to phenibut, suggesting a similar affinity for the GABA receptor.

6. Use Other Anxiolytics to Taper Phenibut Withdrawal

One in particular, Kava, is very effective at mitigating the phenibut hangover. Kava is a safe, non-addictive, anxiolytic herb that can be used at any time during your phenibut withdrawals.

Kava will most certainly not completely eliminate the withdrawal and will not work nearly as well as the medications listed above, but it can at least help to take the edge off and can even be used when/if tapering off of the Phenibut to make things easier.

Kava is commercially available in many forms; “Kava Paste” and “Instant Flavored Kava Root Powder” are simple to consume and mask the bitter taste of raw Kava Kava root powder.

7. Avoid Alcohol At All Costs!

You may also want to avoid drinking alcohol during this phase, for the following reasons:

First of all, a hangover from alcohol is only going to make you feel a lot worse.

On that note: avoid any substances that may give you a hangover or leave you with significantly worse after-effects during your kick.

Secondly, alcohol lowers your inhibitions. Because of this you may find yourself not caring about your kick or your sobriety anymore (especially with the more you drink), and without a second thought you could easily relapse on Phenibut while you are drunk which will only prolong your phenibut withdrawal in the end, make things worse and ruin all of your hard work.

Lastly, alcohol occupies the same receptor as phenibut (GABA B), and drinking alcohol prolongs the next-day phenibut withdrawal and hangover and ultimately, drags out the process.

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Peter Pan - June 26, 2016

I stopped using phenibut abruptly (no taper) after 4 months of daily use at 4000 mg./day. The withdrawal I experienced was a relatively minor annoyance; it was nowhere near as intense as benzo withdrawal. Heck, even most opioids gave me more distressing withdrawal syndromes.

– Tremors & shakes, mostly in the hands when holding something.
– Very early morning awakenings, which doesn’t normally happen to me.
– Constant tinnitus.
– I’d get on the verge of having panic attacks after drinking coffee. But I didn’t actually get a full-fledged panic attack. Normally I can drink coffee without side effect.

I experienced no crushing depression, lethargy, feelings of going crazy, or anything like that. I didn’t even experience sweating during it.

So, for me, phenibut withdrawal was much ado about not much. And I’m somebody who’s always been prone to bad withdrawals.

    Dan - June 26, 2016

    That is…interesting, thanks for sharing.

    Before you stopped, were you still feeling the effects? I’ve never heard of someone avoiding Phenibut withdrawal after quitting cold turkey at high doses, unless they’ve built up a huge tolerance to Phenibut.

Roc - September 16, 2016

So even with the slow taper once your down to 0mg you still have to suffer withdrawals?
I’m down to 750mg now and two weeks ago I’m kind of embarrassed to say how many grams I’ve been taken daily for a little over a year.

    Dan - September 17, 2016


    There’s nothing to be embarrassed about. If I told you how much I’ve taken, you’d be amazed that I’m still alive… Not to mention, you could just pay a quick visit to the bluelight forums to see some insane doses.

    That aside, I’m not a doctor… These articles are based on my own experiences, my friends’ experiences, and a bunch of stuff I’ve read online.

    It’s kind of a trope in the nootropics space at this point, but here’s my suggestions: start with a low dose of phenibut and increase it very slowly over the course of 4-6 weeks. Test one variable (a given dose at a specific time of day with or without a meal). After that, start testing frequency. After that, start testing time of day… Etc.

    If that sounds like a lot of work, it is! Phenibut and other nootropics have the potential to improve our quality of life but only if you take the time to figure out how to make them work for you. A few months of testing and experimentation – a lifetime of knowledge and happiness.

    Good luck.


Jake - August 1, 2017

Phenibut was great for me when I was using it, definitely helped with social anxiety and was a general mood-lifter for me. Honestly felt amazing when I was on it – I was taking roughly 2g per day. Definitely don’t go cold turkey when stopping use, the withdrawal can be rough. I experienced insomnia for a week after stopping abruptly, as well as visual hallucinations for four days after stopping (only in the dark/night though). On top of that, I had hand tremors (mild nuisance, didn’t affect me other than that it was annoying). However, I started up again after a week when the insomnia was really messing me up (500g dose before bed) and tapered myself off over three weeks pretty easily. A taper combined with melatonin to help me sleep on bad nights made the withdrawal bearable, but I think I was over the worst of it anyway, so it’s hard to say definitively for me. I definitely feel like it can be avoided if you space out doses (once every 3-4 days) or at least give yourself as many days rest as you take it for. If you’re taking it daily, be ready for at least some kind of withdrawal – I’ve heard from a friend who was taking double what I was for a longer period of time that baclofen or natural beta blockers like kava do help, but baclofen’s hard to get without a prescription.


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