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Can You Get High on Zoloft?

Oh, Zoloft. You’ve probably heard about this drug due to some of the negative attention it’s received. It’s been accused of causing birth defects, killing user’s sex-drives, and generally wrecking people’s lives.

Beneath the bad press, though, there’s a prescription drug that has provided some genuine benefit for some if its users. The SSRI (selective serotonin reuptake inhibitor) is commonly used to treat depression, OCD, and PTSD. Could it hold some recreational value as well?

What is Zoloft?

Here are a few things you may or may not have known about Zoloft. First off, Zoloft is a brand name; the generic drug name is Sertraline. It was discovered in the 1970s by researchers working at Pfizer:

“In 1977, two men known as Kenneth Koe and Willard Welch also working at Pfizer did some other experiments with different forms of tametraline compounds (mixed tametraline and other drugs) leading them to find “a serotonin reuptake inhibitor” that would later be known as sertraline (Zoloft).”

The researchers learned about the mood-altering properties of the drug, and it was approved for use by the FDA in 1991. In the United States, it is available by prescription and used to treat depression, OCD, panic disorder, anxiety, and several other ailments.

It is commonly compared to Prozac, with the major differences being which kind of patient each drug is prescribed to. Zoloft received some hype during the Ebola scare as a possible treatment, but what about catching a Zoloft high? I decided to survey the experiences of users to learn more.

Why is Zoloft prescribed?

Zoloft is a brand of a drug called Sertraline. It’s an SSRI used to combat major depressive disorder, in addition to OCD, panic disorder, and social anxiety.

By limiting the reuptake of serotonin in the body, it increases its availability and can lead to changes in a user’s mood. It’s a mostly tolerable drug (except when you overdo it) and has several off-label uses that researchers are currently exploring.

Is it approved for other uses?

Zoloft can treat several mood disorders, but also has the potential to help with other ills. There is evidence to suggest it can ease the symptoms of premenstrual syndrome, premature ejaculation, and PTSD as well.

These effects will take some additional study to nail down, and the treatment for premature ejaculation is somewhat hampered by the fact that it requires continuous daily treatment for effects to manifest. Still, these additional uses are interesting and researchers continue to explore them.

Recreational Use

You can find a story here or there of someone taking the drug recreationally and receiving