The Best Nootropic Adaptogens To Beat Stress
Soviet physician and scientist Nikolai Lazarev coined the word “adaptogen” in 1947. It’s derived from the Latin adaptare (to adjust or adapt).
Adaptogenic compounds were developed to improve performance in athletes, military personnel, and government officials. The Soviets were intent on expanding the working capacity of citizens. And bolstering military strength.
At first, Lazarev investigated lab-made synthetics as adaptogens. Then Dr. Israel Brekhman joined Lazarev, and as a team, began the investigation of botanicals for their adaptogenic capabilities. They started with Panax ginseng. Followed by Siberian ginseng (which was local and easier to get).
So successful was their research that by the 1960’s, the Soviet medical establishment assembled a team of 1,200 adaptogen researchers at the Russian Academy of Sciences. Generating nearly 1,500 trials and studies on adaptogens.
The definition of “adaptogen” includes “metabolic regulators (of a natural origin) which increase the ability of an organism to adapt to environmental factors and to avoid damage from such factors.”
Dr. Corneliu Giurgea, the Romanian psychologist who first coined the term “nootropic” included in his definition, “Protects the brain from chemical and physical toxins”, and “Must be non-toxic to humans, nor stimulate or depress the brain”.
So by definition, adaptogens and nootropics share close similarities in their goal and intent.
Adaptogens help your body and brain ‘adapt’ by upregulating or downregulating some function. Bringing your brain back into homeostasis. Into a balanced, healthy, optimized state.
David Tomen, author of Nootropics Expert, made the observation, “When neurohackers who are new to nootropics initially get over the novelty of experimenting with compounds from the racetam-family. Many begin to experiment with adaptogens”.
The beauty of natural adaptogens is they are often easier to find. Have a longer track record of optimizing the brain (i.e. 1,000’s of years). Are often safer (if dosed correctly).
And some are as effective as prescription medications (for treating things like anxiety and depression).
Adaptogens May be the Ultimate Nootropic Supplements
The mechanism of action for adaptogens include:
- Increasing cerebral circulation
- Upregulating nerve growth factor and BDNF
- Modulating brain waves
- Support neuroplasticity
- Boost the synthesis of all the major neurotransmitters
- Improve brain cell signaling
- Prevent brain cell damage and degeneration
- Eliminate heavy metals and food toxins
The end result depending on the adaptogen chosen for your stack can include better alertness, concentration, focus, learning, memory and mood. And less anxiety or brain fog.
So what are these natural substances that can have such a profound effect on cognition and brain health? We’ve identified the most powerful adaptogens below.
Click through to a more detailed report on each of these nootropics. And consider adding at least one or two to your nootropic stack.
Top 8 Nootropic Adaptogens
In Sanskrit, Ashwagandha literally means “the smell of a horse”. Which implies this herb provides the vigor and strength of a stallion.
As a nootropic, Ashwagandha helps with anxiety and depression by reducing the stress hormone cortisol. And enhancing GABA receptors and serotonin in the brain.
Ashwagandha helps regenerate axons, dendrites and synapses. Restoring neural networks and improving memory. And Ashwagandha extract inhibits acetylcholinesterase. The enzyme responsible for breaking down acetylcholine. Boosting cognition, learning and memory.
Ancient Ayurvedic texts talked about Bacopa. It was recommended to devotees to help memorize long passages of text. Today, Bacopa is considered by many to be the best nootropic available.
Bacopa has a significant anxiolytic effect. It appears to modulate brain levels of serotonin which affect mood regulation. The main active components in Bacopa, bacosides A and B improve signaling between neurons. And help rebuild damaged neurons.
One 12-week study found that Bacopa helped improve word recall, attention, memory, focus while learning, and less anxiety.
Ginkgo is one of the oldest species of trees on earth. This “living fossil” dates back 270 million years. It’s so resilient that four Gingko trees survived the atomic explosion at Hiroshima. Only 1,130 meters from the bombs epicenter.
Gingko extract regulates neurotransmitters, protects brain cell degeneration, increases cerebral circulation and is a powerful antioxidant. As a nootropic, Gingko acts as a monoamine oxidase inhibitor (MAOI) which boosts dopamine. It helps eliminate free radicals which prevents damage to brain cells. And increases nitric oxide which dilates blood vessels. Boosting delivery of oxygen and nutrients to energy hungry brain cells.
One study at Liberty University with 262 healthy adults showed that Gingko extract significantly improved verbal and visual recall and memory.
Panax ginseng (Panax means “cure-all” in Greek) is a powerful adaptogen which reduces adrenal fatigue, and boosts GABA. Providing an anti-stress effect.
Ginsenosides increase protein synthesis and the activity of neurotransmitters in the brain. And ginseng stimulates the formation of blood vessels which improves blood circulation in the brain. Improving memory and cognitive abilities.
As a nootropic, Ginseng has developed a reputation for boosting physical and mental energy. A healthy alternative to energy drinks, caffeine and prescription stimulants. One study showed a single dose of Ginseng reduced blood glucose levels. And significantly reduced mental fatigue.
5. Gotu kola
Neurohackers report gotu kola is at least as effective – perhaps even more so – in reducing anxiety and relieving stress than Ashwagandha and Phenibut.
Gotu kola is often called “the student herb” in Bali. Because it increases dendrite and axon growth in brain cells which helps memory. It protects against toxins and oxidative stress. And helps eliminate heavy metals and food additives that cause brain fog, mood swings and migraines.
Gotu kola also helps prevent the breakdown of acetylcholine. Enhancing mood, cognition, memory and learning.
6. Lemon Balm
Swiss Renaissance physician, Paracelsus, called lemon balm the “elixir of life”.
As a nootropic, lemon balm is most commonly used for stress relief, and reduction of panic attacks. Lemon balm also helps with focus, concentration, irritability, depression, and improves memory and learning.
The active component in lemon balm called eugenol is a potent antioxidant. Which acts to boost your body’s natural healing processes by eliminating free radicals that damage brain cells. And Rosmarinic acid in lemon balm provides antidepressant effects by downregulating proteins. Which in turn upregulates BDNF. And boosts dop