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Synergistic Blends: What Supplements Go Well With Phenibut?

I’ve talked about nootropic synergy in multiple posts. It refers to the enhancement of benefits when two or more nootropics are taken together (ie, “1 + 1= 3”).

Although dangerous to mix with some drugs, Phenibut works safely and synergistically with other psychoactive compounds, and it be quite enjoyable to combine it with different herbs, nutrients, or pharmacological agents.

Positive Phenibut Drug Combinations

Many people enjoy mixing phenibut with other compounds that have relaxing effects, such as the herbs magnolia bark, Holy Basil, and kava kava, the amino acid found in green tea, L-theanine, or the essential amino acid L-tryptophan.

MRM Relax-All Supplement

A number of manufacturers market formulas with phenibut in them, such as MRM’s Relax-All, which contains an unspecified amount of phenibut in each dose, along with several other ingredients which also have calming effects.

When I interviewed holistic physician Randy S. Baker, founder and director of the Pacific Center for Integral Health in Santa Cruz, California, about MRM’s Relax-All, he said:

My experience with phenibut is as part of a supplement called Relax-All from MRM. This also has Calcium, Magnesium, Tryptophan, Valerian, Inositol, Ashwagandha, Chamomile and Lemon Balm, though Phenibut is the featured ingredient.

This, of course, makes it impossible for me to know how much of the effect of this supplement is due to the Phenibut versus the other ingredients. I recommend it primarily for muscle spasms, anxiety and insomnia and have generally had very positive feedback in those who have tried it.

As mentioned, it may be dangerous to mix phenibut with alcohol or tranquilizers , yet many people appear to safely enjoy mixing phenibut with small amounts of alcohol.

Phenibut also appears to go well with another GABA derivative called GABOB (gamma-Amino-beta-hydroxybutyric acid, “gamibetal” or “buxamin”).

Using Phenibut With Deprenyl

GABOB has mild sedating qualities that are reported to become more pronounced when mixed with phenibut. I’ve found that phenibut also goes extremely well with a cognitive enhancer known as deprenyl.

Deprenyl (selegiline hydrochloride) is a moderate-level stimulant and antidepressant that has been shown to improve memory, protect the brain against cell damage, alleviate depression, extend the life span of laboratory animals, and heighten sexual desire in both men and women.

Deprenyl is available by prescription in the U.S., and it is primarily prescribed to help people with Parkinson’s disease, memory disorder problems, and sometimes depression.

However, a lot of healthy people also use deprenyl to improve their mental performance, and it is considered by many people to be a “cognitive enhancer,” or a “smart drug.”

Although deprenyl is a prescription drug in the U.S., it can easily be purchased overseas via the internet. I’ve personally found the combination of deprenyl and phenibut to be one of the best antidepressant formulas and social lubricants around.

Smoking Weed and Taking Phenibut

A number of people that I’ve spoken with who suffer from social anxiety, and tried this combination, give it high ratings as well.

However, hands down, I most enjoy combining phenibut with flowers from the forbidden cannabis plant.

I find this healthy combination to be absolutely delightful, and one of the very best ways to relax after a hard day’s work.

Alpha Brain

More recently, I’ve been experimenting with Alpha Brain stacks. Alpha Brain itself is an uber-popular nootropic these days. By itself, it doesn’t do much at all.

But together with other potent nootropics, like Phenibut, it seems to have an additive/synergistic effect.

Namely, I’ve found that taking Alpha Brain with Phenibt helps lower anxiety even further than standalone Phenibut, and seems to slightly curb the next-day Phenibut Hangover (and desire to take it again).

I’ll experiment more with this, as well as other nootropic stacks like Qualia and Thrivous, to see how Phenibut works with natural nootropic stacks.


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