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Methylene Blue as a Nootropic: Full Review

A girl's tongue and lips are colored blue from taking liquid methylene, a nootropic.There are many different nootropics out there to try in the world, including the well-known racetams, vasodilators, stimulants, and even the strangest herbs you’ve ever heard of.  However, in the places where they are discussed, few people have covered ground on the elusive colored agent known as methylene blue (or MB for short).  

Known by lab technicians and biologists as a stain for microscopic observation, MB has been in common use for science since the early 20th century. Only recently has its alternative use as a cognitive enhancer been discovered, and the standard effective dosage remains a mystery to the majority of people who have tried it. 

Nonetheless, it is a very safe substance to ingest, having virtually zero risks or side effects at a reasonable dosage.

Why Should You Take Methylene Blue?

The main point of using MB is to increase concentration and mood, which can be attributed partially to its MAOI effects and influence on general metabolism. Some users have reported a subtle increase of baseline energy, which in itself can help with demanding intellectual tasks.

Another reason to try methylene blue is because it’s relatively inexpensive! If diluted properly, you can make a bottle costing about 4 dollars last for several hundreds or thousands of doses!

This is because the amount you need to take is exceedingly small, it is extremely potent. However, it is still perfectly safe if you accidentally take too much. It is better to take small amounts, as the mental effects only appear at a certain range in the spectrum of dosing.

Where To Buy Methylene Blue

Methylene blue almost always comes in a small bottle as a dark blue liquid, with the intent of being used either in the laboratory as a specimen stain or as a fish tank antifungal. To my knowledge, there aren’t any products on the market that specifically cater to its use as a nootropic.

A good place to find it is Amazon, with many selections of MB, or sites for scientific supplies. Occasionally, you can see it in pet stores as well for use with fish. (Interestingly, the FDA recently declared a shortage of MB, perhaps due to its rise in popularity among the nootropics community).

You’d probably be better off buying the brands marketed as stain, as it will be cheaper and let’s face it: it’s a little weird to be medicating with something meant for fish! One bottle (depending on size and concentration) should cost you about $4 to $12.

What does it look like?

Methylene Blue is one of the more pleasantly-appearing nootropic substances. Instead of coming as a typical white powder in a bag, it usually appears as a dark blue liquid in a small plastic dropper bottle.

A bottle of methylene blue

An important part of the proper use of MB is diluting it properly, which also produces a neat effect as a single drop precipitates into ribbons in water.

Methylene Blue Dosage Levels

Now before you go ahead and start taking drops of MB out of a microscope stain bottle, it’s best to understand that the dosage you actually need is VERY low. In fact, some people have claimed that you only need doses of MB around 500 nanograms, or 500 millionths of one milligram.

However, the standard nootropic dose appears to be around 60 micrograms. I take about one to three micrograms, two to three times a day, and it works for me. In order to take the proper low dose, you need to dilute it quite a lot! Indeed, you’ll need some time and effort to do the math, and you’ll need some measuring supplies.

My method of measurement involves a couple of assumptions: that a milliliter equals about twenty drops, and that my original solution is 15ml 1% methylene blue, which means that each drop is about half of a milligram of MB. Since you have to prepare it yourself, it’s clear that using MB as a nootropic is a new idea that hasn’t been widely marketed yet.

However, it garners attention from those who are looking to build cost-effective stacks. The extremely low dosage and relative cheapness of the substance can allow a single bottle to last years!

How To Dose Methylene Blue

Once you have a solution, you may ask, “What do I do with this liquid stuff?” Okay, well you could in theory mix it in with a beverage or fill certain capsules with it and take it orally, yes. Some people will actually take their methylene blue with their regular drinking water, in fact.

Sticking out tongue after taking methylene blue.This works, but you probably would need a somewhat higher dosage to compensate for the metabolism between your stomach and your bloodstream. The better way is to take it sublingually – under the tongue – with an eyedropper. It’ll