How Modafinil Strikes the Perfect Balance With Dopamine

How does Modafinil affect dopaminethe neurotransmitter that underpins reward?

This is actually a controversial question, partly because Modafinil’s mechanism has been shrouded in mystery until the last decade.

First, a little background info. Increasing dopamine tends to improve working memory. The caveat here is that enhanced dopamine function isn’t going to do much for you if your memory is already optimized. Also, whether or not you realize benefits from enhanced dopamine function is largely genetic.

Returning to the question of how Modafinil affects dopamine: