MK-677 (Ibutamoren) Review for Fat Loss: Dosage Guide & Side Effects

A few months ago, after a minor health scare, my doctor told me that I needed to lose some fat and try to build some muscle to help improve my overall body composition.

Thanks to many hours working in front of a computer, I was a bit overweight and not very strong, which was affecting my ability to do basic things like carrying the groceries to my car or playing with my kids.

Having some health issues in my family, I was concerned that I was going to end up with osteoporosis from weak bones, or diabetes from being overweight when I got older.

While I was nervous about using SARMs (such as human growth hormone) to help me reach my goal, the science behind MK-677 and how it helps the body to release stored fat and build muscle is compelling.

Also known as Ibutamoren, MK-677 is becoming popular with my bodybuilding friends, who say it boosts their metabolism and helps shed excess body fat.

Note: I get my MK-677 from Proven Peptides here.

Things to Consider Before Buying MK-677

As a selective androgen receptor modulator (SARM), MK-677 can do a lot of amazing things.

Taken orally, it can help the body release stored fat, build lean muscle mass, strengthen bones, and can help you live a longer and healthier life.

You might be a good fit for MK-677 if you’re trying to lose weight and get stronger. MK-677 is particularly useful in the older population.

It’s been shown to increase bone strength in adults over the age of 65, to slow functional decline between the ages of 65 and 84, and can also increase bone mineral density in post-menopausal women which decrease the risk of osteoporosis.

Bodybuilders may also get great results from MK-677. When combined with strength training, athletes can see even more pronounced muscle-building effects.

If you have diabetes or already have insulin resistance, this isn’t a good choice for you. To assist with weight loss, you might consider a thermogenic supplement that won’t affect insulin sensitivity.

When I first heard of SARMs, they honestly sounded like steroids. But the more I read, the more I realized they fall more under the umbrella of biohacking than straight bodybuilding.

MK-677: Pros and Cons

MK-677 can help you pack on muscle mass, improve bone health, and strengthen overall body composition.

It comes in a pill, liquid, or powder form and can be taken safely both short and long-term to achieve results.

This supplement is ideal for someone who needs to lose weight for health reasons but wants to maintain and build strength while they’re doing it.

To get the best results, you’ll need to eat a healthy diet and exercise regularly.


  • Available legally when ordered online in the US
  • Clinically-proven to have positive effects in men and women, especially over the age of 65
  • Taken orally as a daily supplement, no need for injections or visits to the doctor
  • Natural supplement that effects growth hormone, not an anabolic steroid


  • When not combined with a healthy diet and regular exercise, participants may see weight gain as a result of taking MK-677
  • MK-677 may lower insulin sensitivity and is not appropriate for someone who is already diabetic.
  • Some users experienced an increase in appetite while taking the hormone
  • As it affects the production of human growth hormone, users may produce a positive result in a drug test for steroids

Main Benefits

Orally supplementing with MK-677 produces several positive effects in the body including:

1. Increase in Serum Concentration of IGF-1 and Growth Hormone

In one study, participants who took MK-677 saw their levels of IGF-1 increased by between 39 and 89%. IGF-1 directly relates to your body’s ability to lose fat and build lean muscle mass.

Its healing properties can also help to build and heal bones, tendons, ligaments, and injuries. Superficially, when your body produces increased levels of IGF-1, you may also see your skin tighten up in areas where it’s loose.

2. Reversal of Nitrogen Wasting

MK-677 can stop the nitrogen wasting effect of a caloric deficit on the body. This means that as you limit your calories and exercise more to lose weight, your body won’t resort to breaking down your muscles for energy.

In study participants, MK-677 helped them to maintain muscle mass and instead use their fat stores as energy.

3. Less Fat Stored

Supplementing with MK-677 can influence where your body stores the calories you eat. In most people, when we eat more calories than we burn in a day some of those calories will be stored as fat.

MK-677 changes that, and instead your body deposits those calories into the muscles, resulting in muscle growth.

4. Increased Bone Mineral Density

Older adults who were given MK-677 as part of a clinical study saw increases in bone density and strength.

This means that the supplement can decrease the risk of developing degenerative bone diseases like osteoporosis and help to maintain bone health in older adults.

banner showing results of taking ibutamoren mk677 in 2017 review

MK-677 Dosage

I weigh about 165 pounds and take between 12-15 mg per day (15mg on