How long does it take Piracetam to work?

Piracetam is a nootropic supplement that has been used by millions of people worldwide.

Piracetam users report a range of benefits for this Racetam such as improving your ability to learn and remember, stimulate attention and concentration, and improve mood and motivation levels.

It acts on the neural network of the brain and increases certain types of activity between neurons. Researchers have found out that it has a protective effect on the cells of the brain and also enables better communication between them.

This part of the brain is accountable for acts, thoughts, reasoning, perception, learning and movement. These mechanisms of action are responsible for many positive effects reported, but what is the real story behind Piracetam?


Piracetam (2-oxo-1-pyrrolidine acetamide) was the first compound developed in racetam “family” of improved cognition nootropic supplements.

It was created synthetically in Belgium in 1964 as a way to improve the corpus callosum of communication. This section of the brain creates a powerful link between the two main brain hemispheres. It is chemically similar to pyroglutamate amino acids, differing only in a single side chain.

Piracetam was produced under many different names over the last 40 years, as Encefalux, Cerebrospan, Nootropil, and Psycotron. Today, Piracetam is used for boosting cognitive function in healthy young brains and fighting against cognitive deterioration.

How Piracetam Works

It is believed to operate by increasing cell membrane’s permeability. Specifically, it improves the distribution and dispersion of oxygen to the brain cells.

In addition to that, it has proved to result in an increase in the traffic to neural tissues. Better circulation keeps them healthy and nourished thereby enhancing tissue protection against normal damage and decay due to aging.

It also helps eliminate waste from cells at a faster pace. Health of the cell membrane is also a protection against hypoxia and can prevent or reduce the risk of brain diseases that result from lack of oxygen including stroke.

Piracetam also affects glucose levels in the brain by inhibiting its reuptake. This results in an increase in glucose metabolism which may lead to a rise in energy and mental alertness.

How long does it take Piracetam to work?

Typically, it takes about one hour for the effects of the stronger sensory perceptions to be felt.

This can continue for 6 to 8 hours. However, for full benefits of Piracetam to be felt, dosage should be continued for two weeks to 1 month.

Users experience an improvement in cognitive function and significant cognitive benefits after 17 days of using Piracetam.

Side effects

No cases of serious adverse effects have ever been reported due to an overdose of Piracetam.

Even in the case of excessive dosage for healthy people (above 5 grams per day), toxic effects are non-existent.

There are few reported side effects, less than 10 percent of users having any adverse reaction. One of the most common is a slight headache.

Other side effects include anxiety, nervousness, feeling agitated, and drowsiness. These are short term effects if at all they occur.

Piracetam Stacks

Stacking is a way to amplify the impact of supplements. By combining complementary elements, the total effect can be greater than the individual benefits.

Due to its lack of side-effects and low inherent toxicity, Piracetam can be added to various nootropics batteries, Piracetam with Vinpocetine, Caffeine, and choline.

Dosage instructions

Piracetam has a broad range of effective doses. A little dose of 400 mg base is the foundation of most of the suggested servings while the median 800 mg is that many people take in one sitting.

There is some disagreement on the ideal Piracetam dose. Many online forums suggest doses upwards of 4 or 5 grams, which is (imo) excessive. However, everyone is different.

Update 2016: Corpina reader Giang shared his experience dosing Piracetam:

Screen Shot 2016-06-14 at 3.53.03 PM

I prefer low doses like 400mg to 800mg because these amounts can be repeated three times a day with zero toxicity effects.


Piracetam plays a significant role in memory and learning. Since 1976, articles in journals like Psychopharmacology began reporting that daily doses of Piracetam above 1,200 mg may help improve your working memory and overall recall.

It takes around an hour for the effects to kick in, and the effects become more noticeable after weeks of use. As with all nootropics, your mileage may vary. Use with caution and you’ll be on the right track to a healthy and sharp brain!

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Click Here to Leave a Comment Below 2 comments
giang - June 14, 2016

Interesting… I hadn’t considered doses that low. The lowest dose of piracetam I’ve taken to provide noticeable benefits is 2g, not 400mg, or 800mg. I guess everyone is different… I’ve heard that it takes a few weeks of dosing to feel the effects. I’ll give it a try. Thanks.

Basant Kumar nayak - November 29, 2017

Thank you for your valuable information


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